Lesions are abnormal damage or changes in tissue of an organism, usually caused by illness or trauma. Lesions are from the Latin laesio "injury". Lesions can occur in plants and animals.
Video Lesion
Jenis
There is no specific classification or naming convention for lesions. Because the definition of the lesions is so widespread, the lesion varieties are almost endless. Although most commonly found in the mouth, in the skin, and in the brain, or anywhere where the tumor can occur, lesions can occur anywhere in the body consisting of soft tissue or osseous material. Generally, lesions may be classified by pattern, size, location, or cause. Lesions are sometimes also named according to the person who found them. Some lesions have special names, such as the Ghon lesion in the lungs of tuberculosis victims, named after the finder of the lesion. The typical skin lesion of varicella zoster virus infection (VZV) is called chicken pox . Dental lesions are usually called dental caries.
Location
Lesions are often grouped by type or location of their network. For example, "skin lesions" or "brain lesions" are named for the tissue in which they are found. If there is any additional significance to areas within the tissues - such as nerve injuries in which different locations correspond to different neurological deficits - they are further classified by location. For example, lesions of the central nervous system are called central lesions, and lesions of the peripheral nervous system are called peripheral lesions. Myocardial lesions result from cardiac muscle damage, and coronary lesions are subtypes depicting lesions in the coronary arteries. The coronary lesions are further classified according to the side of the affected heart and the diameter of the arteries in which they are formed.
Causes and behaviors
If the lesion is caused by the tumor it can be classified as malignant or benign after biopsy analysis. Benign lesions that evolve into malignant lesions are called "premalignant." Cancer lesions are sometimes classified based on their growth kinetics, such as the Lodwick classification, which characterizes classes of bone lesions. Other types of lesions are excitotoxic lesions, which can be caused by amino acid excitants such as kainic acid, which kills neurons through excessive stimulation.
Size and shape
The size of the lesion can be determined as gross or histologically depending on whether they are visible to the naked eye or require a microscope to see. A space-occupied lesion , as the name implies, has a recognizable volume and may override nearby structures, whereas space-less lesions are simply a hole in the network, such as a small area in the brain that turns into fluid after a stroke.
Lesions can also be classified according to the shape they form, as is the case with many ulcers, which can have a bullseye or 'target' look. Coin lesions can be identified in X-rays because they appear like coins that sit on the patient's chest.
Maps Lesion
Research using lesions
Lesions may be useful for researchers in understanding how the brain component produces cognition. Research involving lesions depends on two assumptions: brain damage can affect different aspects of cognition independently, and that locally damaged brain function is identical to the normal brain in the "undamaged" part.
Lesion Sham is the name given to the control procedure during the lesion trial. In fake lesions, the animal can be placed in a stereotaxic device and the electrodes are inserted as in experimental conditions, but no currents are bypassed, and therefore damage to the tissue must be minimal.
Researching with humans
Humans with brain lesions are often the subject of research with the aim of establishing the functioning areas in which their lesions occur.
The lack of use of human subjects is the difficulty in finding subjects who have lesions to areas that the researcher wants to study.
Research with animals
Using animal subjects gives researchers the ability to hurt a particular area on the subject, enabling them to quickly gain a large group of subjects. An example of such research is the mouse hippocampi lesion to establish the hippocampus role in object recognition and object prosperity.
Famous lesions
See also
- Ablation
References
Source of the article : Wikipedia
0 Comments